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Buy Gengraf 25mg Capsules

Cyclosporine 25mg Capsules

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Starting from $5.94

Quick Overview

Brief description of Gengraf 25 mg:


Gengraf 250mg is an immunosuppressive medicine (lessen the efficiency of the immune system), which is widely used around the globe to prevent organ rejection at the time of liver, kidney and heart transplantation. This medicine allows the body to accept the transplanted organ and helps them to function normally and makes it suitable to the body. Gengraf has a higher bioavailability than other immunosuppressant. It decreases the possible susceptibility to infection and cancer during organ transplant. It is also suggested in psoriasis and rheumatoid arthritis.

Quantity Strength Price Unit Price
5 Capsules Gengraf 25mg - Cyclosporine $35.70 $7.14
10 Capsules Gengraf 25mg - Cyclosporine $59.40 $5.94

What is the mechanism of action of Gengraf 25 mg?

Gengraf 25 mg contains the active drug called Cyclosporine, which suppresses cell mediated immune reaction. It inactivates the transcription of cytokine genes present in T cells.  Cyclosporine binds to the protein cyclophillin and forms  a Cyclophillin complex, which inhibits calcineurin which is normally responsible for activating transcription of interleukin2. It also interferes with lymphokine production and interleukin release. Due to the inhibition of interleukin release, the T cell gets deactivated and the immune system gets suppressed.

What are the possible contraindications of Gengraf 25 mg?

  • Don't use Gengraf  if you are hypersensitive to this medicine or its ingredients
  • It is contraindicated in abnormal renal function and malignancies.
  • It is also not suitable in any infectious disease.
  • If you are using any treatment for psoriasis.
  • It is contraindicated in breastfeeding mothers.

What are the drug interactions of Gengraf 25 mg?

There are some drugs that may show interaction with medicine are birth control pills, Allopurinol, coal tar, EzetimibeSulfinpyrazoneTacrolimus,  Temsirolimus and Terbinafine

 What is the storage condition for Gengraf 25 mg?

Gengraf 25 mg should be stored in an airtight container at a room temperature (25ºC). Keep away it away from heat, sunlight and moisture. Keep out of reach of children and pets.


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What is the dosage of Gengraf 25 mg?

Take one capsule of this medicine orally with a glass of water. It should be taken twice daily with or without food. The Dose can be titrated according to the need of patients.

What happens if you miss the dose?

If you miss the dose of this medicine, then take it as soon as possible. But if time gap is more between miss dose and regular dose then skip the miss dose.

What happens in case of over dose?

If you see the overdose, the symptoms produced like collapsing, swelling on legs and pale skin, then immediately call a doctor or take an emergency help. 

What are the possible side effects occour if we are taking Gengraf 25 mg?

The common unwanted effects are produced during the course of treatment are headache, dizziness, insomnia, vomiting, mental or mood changes, severe allergic reaction, confusion and stomach pain.

What precaution we have to follow if we are using Gengraf 25 mg?

  • If you are pregnant or breastfeeding mother, you should not use this medicine.
  • If creatinine levels enhance or acute renal malfunction occurs, then discontinue this medicine.
  • It is necessary to remember that if you are taking Cyclosporin therapy for immune suppression, then you should not take any other medicine for immune suppression. 
  • Avoid excessive exposure to sun rays after taking this medicine.